Scientists find 'hidden brain signatures' of consciousness in vegetative state patients
Scientists find 'hidden brain signatures' of consciousness in vegetative state patients
Scientists find 'hidden brain signatures' of consciousness in vegetative state patients
Scientists in
Cambridge have found hidden signatures in the brains of people in a
vegetative state, which point to networks that could support
consciousness even when a patient appears to be unconscious and
unresponsive. The study could help doctors identify patients who are
aware despite being unable to communicate.
Now, a team of researchers led by scientists at the University of Cambridge and the MRC Cognition and Brain Sciences Unit, Cambridge, have used high-density electroencephalographs (EEG) and a branch of mathematics known as 'graph theory' to study networks of activity in the brains of 32 patients diagnosed as vegetative and minimally conscious and compare them to healthy adults. The findings of the research are published today in the journal PLOS Computational Biology. The study was funded mainly by the Wellcome Trust, the National Institute of Health Research Cambridge Biomedical Research Centre and the Medical Research Council (MRC).
The researchers showed that the rich and diversely connected networks that support awareness in the healthy brain are typically -- but importantly, not always -- impaired in patients in a vegetative state. Some vegetative patients had well-preserved brain networks that look similar to those of healthy adults -- these patients were those who had shown signs of hidden awareness by following commands such as imagining playing tennis.
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